HIPEC stands for Hyperthermic Intra Peritoneal Chemotherapy. It is a specialised form of chemotherapy delivered into the abdomen at high temperatures. It is an innovative method for treatment of cancers which have spread to the peritoneum (a continuous membrane that lines the abdominal cavity and covers the abdominal organs) or originated in the peritoneum. The pre-requisite for HIPEC to work is Cytroreductive Surgery.
Cytoreductive Surgery is a supramajor surgery, which involves removing all visible tumours. Once all the disease is removed, heated chemotherapy is then circulated throughout the abdominal cavity using a special device for one hour. The heat and circulation helps the chemotherapy reach places where conventional chemotherapy doesn’t reach, thus improving disease control and survival. For conventional chemotherapy, the survival is hardly 30% for these cancers which increase almost 70-90% with HIPEC.
Certain cancers which are of peritoneal origin, like Primary Peritoneal Carcinoma, Peritoneal Mesothelioma and PseudomyxomaPeritonei benefit significantly from cytoreductivesurgery and HIPEC. If the disease is far advanced and /or if you are medically unfit to undergo HIPEC surgery, then we also have the option of PIPAC. PIPAC stands for Pressurised Intra Peritoneal Aerosolised Chemotherapy.